Phototoxic contact dermatitis is a sunburn-like skin disorder resulting from direct tissue damage following the ultraviolet light-induced activation of a phototoxic agent.
Common phototoxic agents include tetracylines, antiarrhythmics such as amiodarone, diuretics such as furosemide and chlorothiazide, nonsteroidal anti-inflammatory drugs such as piroxicam and naproxen, phenothiazines and psoralens.
Plants containing furocoumarins such as yarrow, parsley and milfoil may lead to phytophotodermatitis in combination with UV irradiation.
eczema.dermis.netAusgelöst werden diese durch einen direkten Gewebeschaden als Folge einer UV-Licht-induzierten Aktivierung phototoxischer Wirkstoffe.
Häufige phototoxische Stoffe sind Tetrazykline, Antiarrhythmika wie Amiodaron, Diuretika wie Furosemid und Chlorothiazid, Nichtsteroidale Antiphlogistika wie Piroxicam und Naproxen, Phenothiazine und Psoralene.
Furocoumarine enthaltende Pflanzen wie Schafgarbe und Petersilie können in Verbindung mit UV-Licht zu einer Phytophotodermatitis, der sogenannten Wiesengräserdermatitis, führen.
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