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ПредставянеЗащита на личните данниНастройки за поверителност
возникновение
CFTR-Gen
I. gene [ʤi:n] СЪЩ
gene
Gen ср <-s, -e>
defective gene
beschädigtes [o. krankhaft verändertes] Gen
II. gene [ʤi:n] СЪЩ modifier
gene
Gen-
gene test
Gentest м <-(e)s, -s>
CFTR gene СЪЩ (cystic fibrosis transmembrane conductance regulator)
CFTR gene
CFTR-Gen (cystische Fibrose Transmembran-Leitfähigkeitsregulator)
PONS OpenDict

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едноезични примери (не са проверени от PONS редакцията)
For example, there are over 1000 known mutant alleles of the CFTR gene that cause cystic fibrosis.
en.wikipedia.org
In addition, this protein regulates alternate splicing of the CFTR gene.
en.wikipedia.org
Ideally, gene therapy places a normal copy of the CFTR gene into affected cells.
en.wikipedia.org
They started at the crime scene by genetically testing patients with pancreatitis and tracing the process, step by step, to the prime suspect -- that same CFTR gene.
www.post-gazette.com
Human mutations in the CFTR gene might be selected for as a way to survive cholera.
en.wikipedia.org
Примери от интернет (не са проверени от PONS редакцията)
[...]
The success of treatment with psychopharmaceuticals is influenced by many factors, including gene variants that regulate both pharmacokinetic properties of the drug, such as uptake, metabolism and elimination of the substances, and pharmacodynamic properties, i.e. the interaction with the target proteins.
[...]
www.klinikum.uni-muenchen.de
[...]
Der Erfolg einer Behandlung mit Psychopharmaka wird durch viele Faktoren beeinflußt, darunter auch durch Varianten von Genen, die sowohl pharmakokinetische, wie Aufnahme, Metabolismus und Ausscheidung der Substanzen, als auch pharmakodynamische, d.h. die Interaktion mit den Zielproteinen betreffende Eigenschaften der Medikamente regulieren.
[...]
www.klinikum.uni-muenchen.de
[...]
Although pharmacogenetic research in psychiatry is just at its beginning, it has already become clear that at least some polymorphisms in genes of the serotonin receptors, the serotonin transporter and the dopamine receptors play a role in the effects and side effects of psychotropic drugs.
[...]
www.klinikum.uni-muenchen.de
[...]
Obwohl die pharmakogenetische Forschung in der Psychiatrie noch in den Anfängen steht wurde bereits deutlich, daß zumindest einigen Polymorphismen in Genen der Serotonin Rezeptoren, des Serotonin Transporters sowie der Dopamin Rezeptoren eine Rolle bei Wirkung und Nebenwirkung der Substanzen zukommt.
[...]
www.klinikum.uni-muenchen.de
[...]
"This is due, among other things, to the fact that although fungal genomes are about 100 times smaller than the human genome - 40 million base pairs in the genome of Sordaria macrospora, 3,000 million in the human genome - they still encode a similarly large number of genes:
aktuell.ruhr-uni-bochum.de
[...]
„Das liegt unter anderem daran, dass Pilzgenome im Vergleich zum menschlichen Genom zwar ca. 100-mal kleiner sind – 40 Mio. Basenpaare im Genom von Sordaria macrospora, 3.000 Mio. im menschlichen Genom -, aber trotzdem für eine ähnlich große Zahl von Genen kodieren:
aktuell.ruhr-uni-bochum.de
[...]
DNA viruses (herpes viruses, adeno viruses): cloning and mutagenesis of herpesvirus genomes, tropism, trafficking, nucleo-zytoplasmatic transport of capsids, activation and inhibition of cellular genes by viral proteins and miRNAs, systems biology of the infected cell, antiviral therapy through dominant negative mutants and small molecules, vaccine development.
[...]
www.mvp.uni-muenchen.de
[...]
Klonierung und Mutagenese von Herpesvirusgenomen, Tropismus, Trafficking, nukleo-zytoplasmatischer Transport von Capsiden, Aktivierung und Inhibition zellulärer Gene durch virale Proteine und miRNAs, Systembiologie der infizierten Zelle, Antivirale Therapie durch dominant negative Mutanten und small molecules, Impfstoffentwicklung.
[...]
www.mvp.uni-muenchen.de
[...]
cloning and mutagenesis of herpesvirus genomes, tropism, trafficking, nucleo-zytoplasmatic transport of capsids, activation and inhibition of cellular genes by viral proteins and miRNAs, systems biology of the infected cell, antiviral therapy through dominant negative mutants and small molecules, vaccine development.
[...]
www.mvp.uni-muenchen.de
[...]
Klonierung und Mutagenese von Herpesvirusgenomen, Tropismus, Trafficking, nukleo-zytoplasmatischer Transport von Capsiden, Aktivierung und Inhibition zellulärer Gene durch virale Proteine und miRNAs, Systembiologie der infizierten Zelle, Antivirale Therapie durch dominant negative Mutanten und small molecules, Impfstoffentwicklung.
[...]
www.mvp.uni-muenchen.de

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