He ultimately assessed 66 members of her family and reported in 1926 that this was a previously undescribed bleeding disorder that differed from hemophilia.
Hemophilia leads to a severely increased risk of prolonged bleeding from common injuries, or in severe cases bleeds may be spontaneous and without obvious cause.
Rose is a nervous and flighty woman who is haunted by the past and obsessed with destruction; due to her hemophilia, she's closed herself off from the world.